業績(論文・解説)

2023年
(総説)
・Osakabe, N., S. Modafferi, M. L. Ontario, F. Rampulla, V. Zimbone, M. R. Migliore, T. Fritsch, A. S. Abdelhameed, L. Maiolino, G. Lupo, et al. “Polyphenols in inner ear neurobiology, health and disease: From bench to clinics.” Medicina (Kaunas) 59 (2023): 10.3390/medicina59112045.
・Osakabe, N., T. Fushimi, Y. Fujii and V. Calabrese. “Procyanidins and sensory nutrition; do procyanidins modulate homeostasis via astringent taste receptors?” Biosci Biotechnol Biochem (2023): 10.1093/bbb/zbad154.
(原著)
・Muta, O., S. Oyama, M. Odaka, K. Shimizu, S. Katsuragawa, K. Suzuki, T. Fushimi, Y. Fujii, R. Akagi and N. Osakabe. “Cinnamtannin a2, (-)-epicatechin tetramer, attenuates skeletal muscle wasting in disuse atrophy model mice induced by hindlimb suspension.” J Clin Biochem Nutr 73 (2023): 124-30. 10.3164/jcbn.23-12.
・Muta, O., M. Odaka, Y. Fujii, T. Fushimi, H. Sato and N. Osakabe. “Difference in endocrine and behavior between short-term single- and paired-housing mice in metabolic cage.” Neurosci Lett 806 (2023): 137246. 10.1016/j.neulet.2023.137246.
・Homma, T., M. Okamoto, R. Koharazawa, M. Hayakawa, T. Fushimi, C. Tode, Y. Hirota, N. Osakabe, M. Baba and Y. Suhara. “Exploring novel vitamin k derivatives with anti-sars-cov-2 activity.” ACS Omega 8 (2023): 42248-63. 10.1021/acsomega.3c04175.
・Fushimi, T., S. Oyama, R. Koizumi, Y. Fujii and N. Osakabe. “Impact of cyanidin 3-o-glucoside on rat micro-and systemic circulation, possibly thorough angiogenesis.” J Clin Biochem Nutr 72 (2023): 132-38. 10.3164/jcbn.22-50.
ポリフェノール
・越阪部奈緒美、脳腸相関と食・栄養 ”ポリフェノール“ 脳腸相関UPDATE:疾患の予防と健康長寿のための食・栄養・腸環境、「臨床栄養」臨時増刊号142巻6号
(著書)
ポリフェノールの科学 寺尾 純二・下位 香代子(監修)/越阪部 奈緒美・榊原 啓之・中村 宜督・三好 規之・室田 佳恵子(編) 朝倉書店 ISBN:978-4-254-10303-8
(解説)
・越阪部奈緒美、ポリフェノールと感覚栄養学Polyphenol and Sensory Nutrition 2023年 12月、香料、日本香料協会
・越阪部奈緒美、感覚栄養学とチョコレートの真の価値、2023年12月、 月刊フードケミカル

2022年
(原著)
・Suzuki, K., N. Hirashima, Y. Fujii, T. Fushimi, A. Yamamoto, T. Ueno, R. Akagi and N. Osakabe. “Theaflavins decrease skeletal muscle wasting in disuse atrophy induced by hindlimb suspension in mice.” J Clin Biochem Nutr 68 (2021): 228-34. 10.3164/jcbn.20-68.
(総説)
・Osakabe, N., T. Fushimi and Y. Fujii. “Hormetic response to b-type procyanidin ingestion involves stress-related neuromodulation via the gut-brain axis: Preclinical and clinical observations.” Front Nutr 9 (2022): 969823. 10.3389/fnut.2022.969823.
(著書)
越阪部奈緒美、 脳-消化管軸を介したポリフェノールの神経系への作用、ポリフェノールの機能と応用 第8章 脳―消化管軸を介したポリフェノールの神経系への作用 シーエムシー出版 2022年11月30日

2021年
・Ishii Y, Muta O, Teshima T, Hirasima N, Odaka M, Fushimi T, Fujii Y, Osakabe N.Repeated Oral Administration of Flavan-3-ols Induces Browning in Mice Adipose Tissues through Sympathetic Nerve Activation.Nutrients. 2021 Nov 24;13(12):4214. doi: 10.3390/nu13124214.
・Fujii Y, Sakata J, Sato F, Onishi K, Yamato Y, Sakata K, Taira S, Sato H, Osakabe N.Impact of short-term oral dose of cinnamtannin A2, an (-)-epicatechin tetramer, on spatial memory and adult hippocampal neurogenesis in mouse.Biochem Biophys Res Commun. 2021 Dec 31;585:1-7. doi: 10.1016/j.bbrc.2021.11.021.
・Suzuki K, Hirashima N, Fujii Y, Fushimi T, Yamamoto A, Ueno T, Akagi R, Osakabe N. Theaflavins decrease skeletal muscle wasting in disuse atrophy induced by hindlimb suspension in mice.J Clin Biochem Nutr. 2021 May;68(3):228-234. doi: 10.3164/jcbn.20-68.
・Fushimi T, Fujii Y, Koshino H, Inagawa K, Saito A, Koizumi R, Shibata M, Osakabe N.Method for detecting hemodynamic alterations following a single gavage in rats.Exp Anim. 2021 Aug 6;70(3):372-377. doi: 10.1538/expanim.20-0200.
・寺尾 純二, 越阪部 奈緒美 食事由来ポリフェノールのデータベース化と摂取目安量策定の意義, 化学と生物、 Vol.59 No.5 Page. 254 – 261

2020年
・Halib H, Ismail A, Mohd Yusof BN, Osakabe N, Mat Daud ZA. Effects of Cocoa Polyphenols and Dark Chocolate on Obese Adults: A Scoping Review.Nutrients. 2020 12(12):369
・Aihara Y, Fukuda Y, Takizawa A, Osakabe N, Aida T, Tanaka K, Yoshikawa S, Karasuyama H, Adachi T.Visualization of mechanical stress-mediated Ca2+ signaling in the gut using intravital imaging..Biosci Microbiota Food Health. 2020;39(4):209-218.
・Wada R, Takahashi S, Muguruma H, Osakabe N Electrochemical Detection of Curcumin in Food with a Carbon Nanotube-Carboxymethylcellulose Electrode. Anal Sci. 2020;36(9):1113-1118
・Wada R, Takahashi S, Muguruma H, Osakabe N. Electrochemical Detection of Curcumin in Food with a Carbon Nanotube-Carboxymethylcellulose Electrode. Anal Sci. 2020 36(9):1113-1118.
・Koizumi R, Fushimi T, Sato Y, Fujii Y, Sato H, Osakabe N. Relationship between hemodynamic alteration and sympathetic nerve activation following a single oral dose of cinnamtannin A2.Free Radic Res. 2020 22:1-25.
・Nishimura Y, Fukuda Y, Okonogi T, Yoshikawa S, Karasuyama H, Osakabe N, Ikegaya Y, Sasaki T, Adachi T. Dual real-time in vivo monitoring system of the brain-gut axis. Biochem Biophys Res Commun. 2020 524(2):340-345.
・藤井靖之、越阪部奈緒美、素材編 第 5 章 双子葉植物 9 シソ科(オレガノ、セージ、シソ、タイム、ミント他)「スパイス・ハーブの機能と応用」、シーエムシー出版書籍
・藤井靖之、伏見大希、越阪部奈緒美「ポリフェノール~二次機能と三次機能のクロストーク~」、ソフト・ドリンク技術資料、2020 年第 1 号、 79-90、2020
・藤井靖之、越阪部奈緒美 「脳 – 消化管軸を介したプロシアニジンの生体調節作用の解明」、ポリフェノール学会誌 9号、2020

2019年
・Fujii Y , Suzuki K , Adachi T , Taira S, Osakabe N. Corticotropin-releasing hormone is significantly upregulated in the mouse paraventricular nucleus following a single oral dose of cinnamtannin A2 as an (-)-epicatechin tetramer. J Clin Biochem Nutr. In press.
・Tsutsumi A, Horikoshi Y, Fushimi T, Saito A, Koizumi R, Fujii Y, Hu QQ, Hirota Y, Aizawa K, Osakabe N. Acylated anthocyanins derived from purple carrot (Daucus carota L.) induce elevation of blood flow in rat cremaster arteriole. Food Funct. 10, 1726-1735, 2019.
・Muguruma H, Murakami S, Takahashi S, Osakabe N, Inoue H, Ohsawa T. Separationless and Adsorptionless Quantification of Individual Catechins in Green Tea with a Carbon Nanotube-Carboxymethylcellulose Electrode. J Agric Food Chem. 67, 943-954, 2019.
・Murakami S, Takahashi S, Muguruma H, Osakabe N, Inoue H, Ohsawa T. Polyphenol Analysis in Black Tea with Carbon Nanotube Electrode. Anal Sci. doi: 10.2116/analsci.18P516. 682, 2019.

2018年
・Unno T, Osakabe N. Green tea extract and black tea extract differentially influence cecal levels of short-chain fatty acids in rats. Food Sci. Nutr. DOI10.1002/fsn3.607,2018.
・Nakagawa K, Isomoto K, Sakaki T, Kubodera N, Kamao M, Osakabe N, Suhara Y, Okano T. Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice. PLoS One. 13, e0199856, 2018
・Nakagawa Y, Ishimura K, Oya S, Kamino M, Fujii Y, Nanba F, Toda T, Ishii T, Adachi T, Suhara Y, Osakabe N. Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice. PLoS One. 13, e0201203, 2018.
・Fujii Y, Suzuki K, Hasegawa Y, Nanba F, Toda T, Adachi T, Taira S, Osakabe N. Single oral administration of flavan 3-ols induces stress responses monitored with stress hormone elevations in the plasma and paraventricular nucleus. Neurosci Lett.. 682, 106-111, 2018.
・Osakabe N, Terao J. Possible mechanisms of postprandial physiological alterations following flavan 3-ol ingestion. Nutr Rev. 76, 174-186, 2018.

2017年
・Ikeda M, Ueda-Wakagi M, Hayashibara K, Kitano R, Kawase M, Kaihatsu K, Kato N, Suhara Y, Osakabe N, Ashida H. Substitution at the C-3 Position of Catechins Has an Influence on the Binding Affinities against Serum Albumin. Molecules. 22, 2017.
・Kimura K.; Hirota, Y.; Kuwahara, S.; Takeuchi, A.; Tode, C.; Wada, A.; Osakabe, N.; Suhara, Y. Synthesis of novel synthetic vitamin K analogues prepared by introduction of a heteroatom and a phenyl group that induce highly selective neuronal differentiation of neuronal progenitor cells. 312-314J. Med. Chem. 60, 2591-2596, 2017
・Ito M, Kudo N, Miyake Y, Imai T, Unno T, Yamashita Y, Hirota Y, Ashida H, Osakabe N.Flavan 3-ol delays the progression of disuse atrophy induced by hindlimb suspension in mice. Exp Gerontol.98,120-123, 2017.
・越阪部奈緒美 脳-消化管軸を介したプロシアニジンの生理作用の発現, 生物工学会誌, 95, 312-314, 2017

2016年
・Adachi T, Kakuta S, Aihara Y, Kamiya T, Watanabe Y, Osakabe N, Hazato N, Miyawaki A, Yoshikawa S, Usami T, Karasuyama H, Kimoto-Nira H, Hirayama K, Tsuji NM. Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo. Front Immunol. 7, 2016.
・Saito A, Inagawa K, Ebe R, Fukase S, Horikoshi Y, Shibata M, Osakabe N. Onset of a hypotensive effect following ingestion of flavan 3-ols involved in the activation of adrenergic receptors.Free Radic Biol Med.99,584-592,2016
・Ushiama S, Ishimaru Y, Narukawa M, Yoshioka M, Kozuka C, Watanabe N, Tsunoda M, Osakabe N, Asakura T, Masuzaki H, Abe K. Catecholamines Facilitate Fuel Expenditure and Protect Against Obesity via a Novel Network of the Gut-Brain Axis in Transcription Factor Skn-1-deficient Mice. EBioMedicine. 8, 60-71, 2016
・Saito A, Nakazato R, Suhara Y, Shibata M, Fukui T, Ishii T, Asanuma T, Mochizuki K, Nakayama T, Osakabe N.The impact of theaflavins on systemic-and microcirculation alterations: The murine and randomized feasibility trials.J Nutr Biochem. 32, 107-14, 20166
・越阪部奈緒美 ポリフェノールパラドックス-生体利用性と機能性の矛盾 化学と生物I54,726-731, 2016
越阪部奈緒美 脳腸相関と食品:ポリフェノール 臨床栄養 128, 820-827, 2016

タイトルとURLをコピーしました